Cockcroft–Gault Calculator

About this calculator

The Cockcroft–Gault equation estimates creatinine clearance (CrCl), a proxy for kidney filtration rate, as CrCl = [(140 − age) × weight] / (72 × serum creatinine), multiplied by 0.85 for female patients (age in years, weight in kg, serum creatinine in mg/dL). Unlike the newer eGFR formulas, Cockcroft–Gault uses actual body weight and was specifically validated for adjusting drug doses, which is why it remains the reference method in many drug-dosing guidelines even though other formulas are considered more accurate for diagnosing kidney disease.

Physicians and hospital pharmacists use it to adjust doses of renally-cleared medications (such as certain antibiotics, anticoagulants, and chemotherapy agents) to avoid toxic accumulation in patients with reduced kidney function, nephrologists use it alongside other renal function markers, and nursing and pharmacy students learn it as a standard formula in clinical pharmacology coursework.